how to test for glp 1 deficiency Do Fasting GLP-1 and GIP Levels Predict the Initial Pharmacological Response Semaglutide and Tirzepatide? Nutritional Deficiencies with weekly GLP-1
Description
Common side effects - including nausea and gastrointestinal discomfort - are most prominent in early weeks and often reduce over time
veterans published in February 2026 in JAMA Ophthalmology reported a roughly 2-fold higher NAION risk among semaglutide initiators, while also noting that the absolute risk remained low
Mounjaro ~22.5% average body weight loss Significant weight reduction Improves blood sugar levels Clinically proven weight loss Wegovy ~16.9% average body weight loss Boosts metabolic & cardiovascular health Proven, long-established safety profile Weekly injection, easy to use
By mimicking the natural GLP-1 hormone, the medication helps your pancreas release the right amount of insulin when blood sugar is high and slows down the livers production of excess glucose

The table below highlights key operational, clinical, and accessibility differences that may inform provider or patient choice

These medications work by mimicking the effects of the natural hormone GLP-1, which plays a crucial role in regulating appetite, blood sugar, and metabolism